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Volume:2 Issue:7 Number:332 ISSN#:2563-5476
Author Verified
Meta-analysis
ACE Report #4244
Ace Report Cover General Orthopaedics

Major orthopedic surgery: Low-molecular-weight heparins vs other anticoagulants


How to Cite

OrthoEvidence. Major orthopedic surgery: Low-molecular-weight heparins vs other anticoagulants. ACE Report. 2013;2(7):332. Available from: https://myorthoevidene.com/AceReport/Report/4244

Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:N/A

Comparative Effectiveness of Low-Molecular-Weight Heparins versus Other Anticoagulants in Major Orthopedic Surgery: A Systematic Review and Meta-analysis

Pharmacotherapy. 2012 Sep;32(9):799-808. doi: 10.1002/j.1875-9114.2012.01106.x. Epub 2012 Jun 28

Contributing Authors: DM Sobieraj CI Coleman V Tongbram W Chen J Colby S Lee J Kluger S Makanji A Ashaye CM White

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Synopsis

This meta-analysis and systematic review included 37 studies comparing low molecular-weight heparins (LMWHs) to other anticoagulants in patients undergoing major orthopedic surgery. The results indicated that LMWHs were more effective and also led to fewer cases of bleeding than unfractionated heparins. LMWHs led to fewer cases of deep vein thrombosis events than vitamin K antagonists, but resulte...

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