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Indometacin does not reduce the incidence of heterotopic ossification
November 2014
Indometacin does not reduce the incidence of heterotopic ossification
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Indometacin as prophylaxis for heterotopic ossification after the operative treatment of fractures of the acetabulum
J Bone Joint Surg Br. 2006 Dec;88(12):1613-7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
127 patients with displaced fractures of the acetabulum were included in this study to examine the effectiveness of indometacin in reducing the incidence of heterotopic ossification (HO). Patients were randomized to receive indometacin sustained released (75 mg) or placebo daily for 6 weeks. After 3 months, there was no significant difference between the two groups for the incidence of HO and rate...
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