TKA: Topical fibrin spray significantly reduces total blood loss
Reducing blood loss in primary knee arthroplasty: a prospective randomised controlled trial of tranexamic acid and fibrin sprayKnee. 2012 Aug;19(4):295-8. Epub 2011 Jul 5
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66 patients undergoing navigated, cemented total knee arthroplasty were randomized to one of three groups to compare the efficacy of two different haemostatic agents on total blood loss. Patients received a 10mg/kg bolus of tranexamic acid intravenously, topical fibrin spray, or no additional haemostatic treatment (control). The results indicated that both haemostatic agents produced a reduction i...
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