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TKA: Topical fibrin spray significantly reduces total blood loss

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Ace Report Cover
May 2013

TKA: Topical fibrin spray significantly reduces total blood loss

Vol: 2| Issue: 4| Number:20| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Reducing blood loss in primary knee arthroplasty: a prospective randomised controlled trial of tranexamic acid and fibrin spray

Knee. 2012 Aug;19(4):295-8. Epub 2011 Jul 5

Contributing Authors:
JS McConnell S Shewale NA Munro K Shah AH Deakin AW Kinninmonth

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Synopsis

66 patients undergoing navigated, cemented total knee arthroplasty were randomized to one of three groups to compare the efficacy of two different haemostatic agents on total blood loss. Patients received a 10mg/kg bolus of tranexamic acid intravenously, topical fibrin spray, or no additional haemostatic treatment (control). The results indicated that both haemostatic agents produced a reduction i...

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