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TKA: Epoetin alfa leads to improved hematological parameters and lower risk of transfusion

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Ace Report Cover
August 2013

TKA: Epoetin alfa leads to improved hematological parameters and lower risk of transfusion

Vol: 2| Issue: 7| Number:517| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Preoperative Epoetin Alfa vs Autologous Blood Donation in Primary Total Knee Arthroplasty

J Arthroplasty. 2006 Aug;21(5):628-35

Contributing Authors:
A Deutsch J Spaulding RE Marcus

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Synopsis

50 patients with pretreatment hemoglobin level of 100 to 130 g/L who were undergoing primary total knee reconstruction were randomized to receive standard care using preoperative autologous blood donation (PAD) or recombinant human erythropoietin (epoetin alfa) at 40 000 U (preoperative day 14). Blood counts were done every day for up to 5 days after the operation. From the day of surgery to two d...

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