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Knee ACI: No clinical outcome differences between periosteal and collagen membrane cover

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Ace Report Cover
August 2013

Knee ACI: No clinical outcome differences between periosteal and collagen membrane cover

Vol: 2| Issue: 7| Number:503| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

A prospective, ranomised study comparing two techniques of autologous chondrocyte implantation for osteochondral defects in the knee: Periosteum covered versus type I/III collagen covered

Knee. 2006 Jun;13(3):203-10. Epub 2006 Apr 27

Contributing Authors:
CR Gooding W Bartlett G Bentley JA Skinner R Carrington A Flanagan

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Synopsis

68 patients with symptomatic articular cartilage defects in the knee were randomized to receive autologous chondrocyte implantation with a periosteal cover (ACI-P) or a type I/III collagen membrane (ACI-C). After a follow up period of 24 months, there was no significant difference in clinical outcome between the two groups. However, a significant amount of the ACI-P patients required shaving of a ...

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