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Volume:1 Issue:5 Number:83 ISSN#:2563-5476
Author Verified
ACE Report #335
Ace Report Cover Arthroplasty

Rivaroxaban is an adequate treatment for thromboprophylaxis after total knee arthroplasty

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): A randomised trial

Lancet. 2009 May 16;373(9676):1673-80. Epub 2009 May 4

Contributing Authors: AG Turpie MR Lassen BL Davidson KA Bauer M Gent LM Kwong FD Cushner PA Lotke SD Berkowitz TJ Bandel A Benson F Misselwitz WD Fisher RECORD4 Investigators

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3148 patients who underwent total knee arthroplasty (TKA) were randomized to thromboprophylaxis using either orally administer rivaroxaban or subcutaneous injection of enoxaparin. This study assessed the efficacy of thromboprophylaxis treatment with rivaroxaban and assessed its non-inferiority to enoxaparin. The results of this study indicated that rivaroxaban was superior in comparison to enoxapa...

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