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High molecular weight biological fermentation hyaluronan advantageous in knee OA treatment
August 2013
High molecular weight biological fermentation hyaluronan advantageous in knee OA treatment
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee
Osteoarthritis Cartilage.2006..14.154-162.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
321 patients with knee osteoarthritis were randomised to receive treatment from one of two forms of high molecular weight hyaluronan. The first group received a high molecular weight hyaluronan produced by biological fermentation (Bio-HA), while the second group received an avian-derived hyaluronan that uses cross-linking. The primary outcome was the effectiveness of the hyaluronan intervention. R...
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