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Glucosamine sulphate, a controversial treatment for osteoarthritis

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Ace Report Cover
May 2013

Glucosamine sulphate, a controversial treatment for osteoarthritis

Vol: 2| Issue: 4| Number:78| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Effect of glucosamine sulphate on joint space narrowing, pain, and function in patients with hip osteoarthritis: Subgroup analyses of a randomized controlled trial

Osteoarthritis Cartilage. 2009 Apr;17(4):427-32. Epub 2008 Oct 9

Contributing Authors:
RM Rozendaal EJ Uitterlinden GJ van Osch EH Garling SP Willemsen AZ Ginai JA Verhaar H Weinans BW Koes SM Bierma-Zeinstra

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Synopsis

222 patients with osteoarthritis of the hip were randomized to receive 1500 mg of glucosamine sulphate (GS) or a placebo daily to determine which subgroups would benefit the most from GS treatment. The 24 month results from this trial indicated that GS treatment provided no improvements in WOMAC pain and function scores or joint space narrowing when compared to the placebo group. Therefore, glucos...

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