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Cross-linked formulation of hyaluronic acid provides long term pain relief

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Ace Report Cover
August 2013

Cross-linked formulation of hyaluronic acid provides long term pain relief

Vol: 2| Issue: 7| Number:435| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

A multicenter, randomized controlled trial comparing a single intra-articular injection of Gel-200, a new cross-linked formulation of hyaluronic acid, to phosphate buffered saline for treatment of osteoarthritis of the knee

Osteoarthritis Cartilage. 2012 May;20(5):350-6. Epub 2012 Feb 1

Contributing Authors:
V Strand HS Baraf PT Lavin S Lim H Hosokawa

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Synopsis

379 patients with osteoarthritis of the knee who had joint aspiration were randomized to receive a single injection of Gel-200 (new cross-linked hyaluronic acid product) or phosphate buffered saline (PBS) solution. Results from 13 week follow-up revealed that patients who received Gel-200 had significantly better pain scores and functions. Additionally, the two groups did not significantly differ ...

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