RA: Addition of etanercept to methotrexate increases remission rates
RA: Addition of etanercept to methotrexate increases remission rates
Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): A randomised, double-blind, parallel treatment trial
Lancet. 2008 Aug 2;372(9636):375-82. Epub 2008 Jul 16Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
542 patients with adult-onset rheumatoid arthritis were randomized to either receive a combination treatment of both etanercept and methotrexate, or just treatment with methotrexate. The results at 1 year indicated that the combination of etanercept and methotrexate resulted in high remission rates and was effective in arresting radiographic progression of joint damage.
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