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RCT
ACE Report #2815
Ace Report Cover Arthroplasty

Epoetin-alpha injection effective in reducing need for allogenic blood transfusions


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Pre-operative injections of epoetin-alpha versus post-operative retransfusion of autologous shed blood in total hip and knee replacement - prospective randomised clinical trial

J Bone Joint Surg Br. 2008 Aug;90(8):1079-83

Contributing Authors: AF Moonen BJ Thomassen NT Knoors JJ van Os AD Verburg P Pilot

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Synopsis

100 patients scheduled to undergo elective total hip or knee replacement, presenting with osteoarthritis were randomized to either receive pre-operative injections of epoetin-alpha (Eprex) or post-operative autologous blood retransfusions using the Bellovac system. These patients exhibited pre-operative haemoglobin levels between 10.0 g/dl and 13.0 g/dl. The results indicated that injections of ep...

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