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Opioid-Sparing Ketorolac Protocol for Pain Control After Meniscus Surgery
October 2025
Opioid-Sparing Ketorolac Protocol for Pain Control After Meniscus Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
An Opioid-Sparing Pain Protocol of Intravenous and Oral Ketorolac Reduces Opioid Consumption and Pain Levels After Arthroscopic Meniscus Surgery: A Prospective, Randomized Controlled Trial.
Arthroscopy . 2025 Jun;41(6):1989-2001.e1.Synopsis
Forty-eight patients with meniscal pathology undergoing arthroscopic meniscus surgery were randomized to receive oxycodone-acetaminophen alone (n = 25) or a ketorolac protocol—30 mg IV intraoperatively plus 10 mg orally every 6 hours for 3 days, with rescue oxycodone-acetaminophen (n = 23). The primary outcomes were VAS pain and opioid consumption (converted to MMEs) during postoperative days (POD...
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