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Platelet-Rich Plasma Injections Are Inferior to Corticosteroid Injections for Short-Term Pain Relief

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Ace Report Cover
October 2025

Platelet-Rich Plasma Injections Are Inferior to Corticosteroid Injections for Short-Term Pain Relief

Vol: 307| Issue: 10| Number:16| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Platelet-Rich Plasma Injections Are Inferior to Corticosteroid Injections for Short-Term Pain Relief: A Prospective, Double-Blinded, Randomized Controlled Trial.

J Arthroplasty . 2025 Jul;40(7S1):S59-S64.

Contributing Authors:
SS Bains GN Swartz R Katanbaf J Nace C Bennett MA Mont RE Delanois

Synopsis

Fifty-two patients with symptomatic KL II–III knee osteoarthritis (OA) were randomized to receive platelet-rich plasma (PRP) (n=26) or corticosteroid (CS) (n=26). The primary outcome was change in VAS pain. Secondary outcomes were NPRS pain, KOOS JR, and WOMAC. Outcomes were assessed at baseline, 6 weeks, and 3 months. Overall, the results of the study revealed that CS produced significantly large...

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