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tDCS Enhances Short-Term Pain & Walking Outcomes When Combined with TENS in Mild Knee Osteoarthritis

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Ace Report Cover
October 2025

tDCS Enhances Short-Term Pain & Walking Outcomes When Combined with TENS in Mild Knee Osteoarthritis

Vol: 307| Issue: 10| Number:30| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Transcranial direct current stimulation enhances the efficacy of wearable transcutaneous electrical nerve stimulation for mild knee osteoarthritis in the middle-aged person: a randomized controlled trial.

BMC Musculoskelet Disord . 2025 Jul 15;26(1):684.

Contributing Authors:
CY Xia HZ Niu XW Zhang SY Cai YJ Fan TP Xie PX Dong XT Zu ZL Su XS Lu YG Hao M Su

Synopsis

One hundred and fifteen patients with mild KOA were randomized to receive wearable transcutaneous electrical nerve stimulation (TENS) + active transcranial direct current stimulation (tDCS) (n=58) or TENS + sham tDCS (n=57). The primary outcome was Brief Pain Inventory (BPI). Secondary outcomes included VAS pain, step length, cadence, 6-minute walking test (6MWT), active knee ROM, and quadriceps s...

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