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Atelocollagen vs. Prolotherapy in Partial-Thickness Supraspinatus Tears:
October 2025
Atelocollagen vs. Prolotherapy in Partial-Thickness Supraspinatus Tears:
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Atelocollagen vs. Prolotherapy in Partial-Thickness Supraspinatus Tears: A Prospective Randomized Controlled Trial with MRI-Confirmed Outcomes.
Pain Physician . 2025 Jul;28(4):299-306.Synopsis
Thirty-four patients with partial-thickness supraspinatus tears were randomized to ultrasound-guided prolotherapy with 20% dextrose (n=17) or atelocollagen injections (n=17), each delivered in three weekly sessions. The primary outcome was change in pain (VAS) to 3 months. Secondary outcomes were K-SPADI and SCSS at 1 and 3 months, and MRI-based changes in tear status from baseline to 3 months. Ov...
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