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Saccharomyces Boulardii Improves Clinical & Paraclinical Indices In Overweight Knee OA Patients
August 2025
Saccharomyces Boulardii Improves Clinical & Paraclinical Indices In Overweight Knee OA Patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Saccharomyces boulardii improves clinical and paraclinical indices in overweight/obese knee osteoarthritis patients: a randomized triple-blind placebo-controlled trial.
Eur J Nutr . 2024 Sep;63(6):2291-2305.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy patients with mild to moderate knee osteoarthritis and a BMI of 25–40 kg/m² were randomized to receive Saccharomyces boulardii probiotic capsules (n=35) or placebo (n=35) for 12 weeks. The primary outcome was change in pain intensity measured by the WOMAC pain score. Secondary outcomes included VAS pain scores, acetaminophen intake, serum hs-CRP, MDA, TAC, and quality of life scores. Outco...
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