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Chlorhexidine Bathing Has Limited Impact on Preventing Infection After Fracture Surgery
August 2025
Chlorhexidine Bathing Has Limited Impact on Preventing Infection After Fracture Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Chlorhexidine Gluconate Bathing Has Limited Ability to Prevent Surgical Site Infection Following Operative Fixation of Extremity and Pelvic Fractures.
J Bone Joint Surg Am . 2025 Jun 18;107(Suppl 1):36-42.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ten thousand one hundred three patients with open or closed extremity or pelvic fractures were randomized as part of a cluster-randomized crossover trial to receive either a preoperative chlorhexidine gluconate (CHG) bath (n=2,674) or no CHG bath (n=7,429). The primary outcome of interest was surgical site infection (SSI) within 90 days of surgery. Secondary outcomes included SSI within 1 year, St...
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