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Efficacy of Botulinum Toxin Injections for Neck and Shoulder Myofascial Pain

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Ace Report Cover
August 2025

Efficacy of Botulinum Toxin Injections for Neck and Shoulder Myofascial Pain

Vol: 307| Issue: 8| Number:55| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy of botulinum toxin in myofascial pain in neck and shoulder-systematic review and meta-analysis.

Int J Rehabil Res . 2025 Jun 1;48(2):83-89.

Contributing Authors:
M Saltychev A Miikkulainen J Juhola

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Synopsis

Seven randomized controlled trials including 261 patients with myofascial pain of the neck and shoulder were included in this systematic review and meta-analysis comparing botulinum toxin A (BTX-A) injections with saline injections. Pooled outcomes of interest included pain reduction (VAS/NRS). The pooled weighted mean difference favored BTX-A, but the difference did not meet the threshold for cli...

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