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Efficacy of Cryoneurolysis on Chronic Pain in Patients with Knee Osteoarthritis
July 2025
Efficacy of Cryoneurolysis on Chronic Pain in Patients with Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of Cryoneurolysis on Chronic Pain in Patients with Knee Osteoarthritis: A Double-blinded Randomized Controlled Sham Trial.
Anesthesiology . 2025 Jun 1;142(6):1114-1126.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty-seven patients with chronic knee osteoarthritis were randomized to receive either cryoneurolysis (n=44) or a sham procedure (n=43). Both groups subsequently participated in an 8-week structured exercise program (GLA:D). The primary outcome was the difference in average pain over the previous 24 hours at 14 days post-intervention. Secondary outcomes included worst and least pain, pain during...
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