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Scaffold Augmentation vs Microfracture for Knee Cartilage Repair: No Short-Term Superiority Found
August 2025
Scaffold Augmentation vs Microfracture for Knee Cartilage Repair: No Short-Term Superiority Found
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Does scaffold enhancement show significant superiority over microfracture alone for treating knee chondral defects? A systematic review and meta-analysis of randomised clinical trials.
Knee Surg Sports Traumatol Arthrosc . 2025 Jun;33(6):2027-2043.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ten RCTs including 378 patients with focal knee chondral/osteochondral defects were included in this systematic review and meta‑analysis comparing microfracture plus scaffold augmentation versus microfracture alone. Pooled outcomes of interest included IKDC, KOOS, VAS, and MOCART. Across 12–24 months, pooled effects showed no significant superiority of scaffold augmentation over microfracture on I...
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