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Kinematic vs Mechanical Alignment in TKA Shows No Meaningful Benefit
August 2025
Kinematic vs Mechanical Alignment in TKA Shows No Meaningful Benefit
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Kinematic Alignment Does Not Result in Clinically Important Improvements After TKA Compared With Mechanical Alignment: A Meta-analysis of Randomized Trials.
Clin Orthop Relat Res . 2025 Jun 1;483(6):1020-1030.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Twelve randomized controlled trials including 1033 patients undergoing primary TKA for knee osteoarthritis were included in this systematic review and meta-analysis comparing kinematic alignment versus mechanical alignment. Pooled outcomes of interest included functional scores (OKS/WOMAC), Forgotten Joint Score (FJS), EQ-5D, VAS, and ROM in flexion and extension. Across nine pooled studies, funct...
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