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Spinal Manipulation Reduces Chronic Low Back Pain, Hyperalgesia, and Catastrophizing
July 2025
Spinal Manipulation Reduces Chronic Low Back Pain, Hyperalgesia, and Catastrophizing
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Reduction of Chronic Primary Low Back Pain by Spinal Manipulative Therapy is Accompanied by Decreases in Segmental Mechanical Hyperalgesia and Pain Catastrophizing: A Randomized Placebo-controlled Dual-blind Mixed Experimental Trial.
J Pain . 2024 Aug;25(8):104500Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ninety-eight patients with chronic primary low back pain were randomized to receive either spinal manipulative therapy (SMT; n=49) or a validated placebo intervention (n=49) delivered 12 times over 4 weeks. The primary outcome was change in pain intensity and disability. Secondary outcomes included pressure pain thresholds (PPTs), pain catastrophizing, central sensitization, depression, and anxiet...
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