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Comparing The Efficacy And Safety Of Oral Versus Intravenous Tranexamic Acid In Spine Surgery
July 2025
Comparing The Efficacy And Safety Of Oral Versus Intravenous Tranexamic Acid In Spine Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparing the efficacy and safety of oral versus intravenous tranexamic acid in spine surgery: a systematic review and meta-analysis of randomized controlled trials.
Neurosurg Rev . 2025 May 31;48(1):470.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Four randomized controlled trials including 717 patients undergoing spine surgery were included in this systematic review and meta-analysis comparing oral versus intravenous tranexamic acid (TXA). Pooled outcomes of interest included intraoperative and total blood loss, hemoglobin and hematocrit drop, transfusion rates, postoperative drainage volume, and complications such as DVT and infection. Th...
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