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Rivaroxaban Versus Enoxaparin As Thromboprophylaxis In Degenerative Spine Surgery
July 2025
Rivaroxaban Versus Enoxaparin As Thromboprophylaxis In Degenerative Spine Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Rivaroxaban versus enoxaparin as thromboprophylaxis in degenerative spine surgery: a randomized blinded non-inferiority study.
Eur Spine J . 2025 May;34(5):1926-1933.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Two hundred twenty patients undergoing degenerative spine surgery were randomized to receive either enoxaparin 40 mg subcutaneously once daily (n=110) or rivaroxaban 10 mg orally once daily (n=110). The primary outcome was the incidence of venous thromboembolism (VTE) (DVT and PE). Secondary outcomes included reoperation rate, length of hospital stay, surgical site infection, CSF leakage, and oth...
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