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IV Dexamethasone Temporarily Raises Glucose and Eases Pain After TKA in Type-2 Diabetes
July 2025
IV Dexamethasone Temporarily Raises Glucose and Eases Pain After TKA in Type-2 Diabetes
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Intravenous Dexamethasone Transiently Elevates Blood Glucose Levels and Reduces Pain After TKA in Patients with Type-2 Diabetes Mellitus: A Randomized Controlled Study.
J Bone Joint Surg Am . 2025 May 21;107(10):1073-1081.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty-three patients with well-controlled type-2 diabetes mellitus undergoing primary total knee arthroplasty were randomized to receive either intravenous dexamethasone (n=42) or placebo (n=41). The primary outcome was postoperative blood glucose levels. Secondary outcomes included insulin requirements, postoperative pain (at rest and during activity), and postoperative nausea and vomiting (PONV...
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