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Unilateral vs Bilateral Pedicle Screw Fixation in Elderly Lumbar Fusion

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October 2025

Unilateral vs Bilateral Pedicle Screw Fixation in Elderly Lumbar Fusion

Vol: 307| Issue: 10| Number:70| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Clinical efficacy and quality of life in elderly patients with lumbar degenerative disease treated with TLIF combined with unilateral pedicle screw fixation: a randomized controlled study.

J Orthop Surg Res . 2025 Apr 26;20(1):420.

Contributing Authors:
CP Li KK Feng XB Xiang KY Gao WW Zhang ZY Nie D Zhao WX Liao GR Cao

Synopsis

One hundred twelve patients with lumbar degenerative disease (LDD) were randomized to TLIF (transforaminal lumbar interbody fusion)+unilateral pedicle screw fixation (UPSF) (n=54) or TLIF+bilateral pedicle screw fixation (BPSF)(n=58). The primary outcome of interest was health-related quality of life (SF-36 PCS/MCS); secondary outcomes included operative time, blood loss, time to ambulation, lengt...

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