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Opioid-Free Perioperative Pain Protocol Is Noninferior to Opioid-Containing Management
June 2025
Opioid-Free Perioperative Pain Protocol Is Noninferior to Opioid-Containing Management
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
An Opioid-Free Perioperative Pain Protocol Is Noninferior to Opioid-Containing Management: A Randomized Controlled Trial.
J Bone Joint Surg Am. 2025 Apr 2;107(7):665-677.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Three hundred fifteen patients undergoing five common elective orthopedic procedures were randomized to receive either an opioid-free perioperative pain management protocol (n=157) or an opioid-containing protocol (n=158). The primary outcome was the numeric rating scale (NRS) for pain at 24 hours postoperatively. Secondary outcomes included pain levels at other time points (6 and 12 hours; 2 week...
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