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Effect of Oral Caffeine on Postoperative Opioid Use in Adolescent Idiopathic Scoliosis Patients

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Ace Report Cover
June 2025

Effect of Oral Caffeine on Postoperative Opioid Use in Adolescent Idiopathic Scoliosis Patients

Vol: 307| Issue: 6| Number:5| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Can oral caffeine decrease postoperative opioid consumption following posterior spinal fusion in adolescent idiopathic scoliosis? A randomized placebo-controlled trial.

N Am Spine Soc J . 2025 Jan 13:21:100582.

Contributing Authors:
A Stuedemann RM Schwend KA Shaw N Saddler M Huston M Benvenuti J Leamon AK Sherman J Anderson

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Synopsis

Fifty-one patients aged 12–17 years with adolescent idiopathic scoliosis undergoing posterior spinal fusion were randomized to receive either oral caffeine (n=24) or placebo (n=27). The primary outcome of interest was total postoperative opioid consumption (MME). Secondary outcomes included pain scores, number of diazepam requests, average heart rate, average systolic blood pressure, and length of...

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