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Efficacy & Safety of Topical Tranexamic Acid in Elderly Hip Fractures Undergoing Surgical Treatment
August 2025
Efficacy & Safety of Topical Tranexamic Acid in Elderly Hip Fractures Undergoing Surgical Treatment
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy and Safety of Topical Tranexamic Acid in Elderly Hip Fractures Undergoing Surgical Treatment: Meta-Analysis of Randomized Controlled Trials.
Clin Orthop Surg . 2025 Feb;17(1):16-28. doi: 10.4055/cios24184.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Nine randomized controlled trials including 1,024 elderly patients with hip fractures were included in this systematic review and meta-analysis comparing topical tranexamic acid (TXA) with intravenous TXA or placebo. Pooled outcomes of interest included transfusion rates, transfused blood units, hemoglobin drop, hematocrit loss, total blood loss, drain output, hospital stay, surgery duration, deep...
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