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AAOS 2025: Does Melatonin Improve Sleep Following Primary Total Hip Arthroplasty
April 2025
AAOS 2025: Does Melatonin Improve Sleep Following Primary Total Hip Arthroplasty
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Does Melatonin Improve Sleep Following Primary Total Hip Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial
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CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
One hundred thirty-nine patients undergoing elective primary total hip arthroplasty were randomized to receive melatonin 5 mg nightly (n=75) or placebo (n=64) for 14 days after surgery. The primary outcome of interest was sleep disturbance, assessed using PROMIS-SD scores on postoperative day 14. Secondary outcomes included nightly pain scores, hours of sleep, nighttime awakenings, and Epworth Sle...
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