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Influence of Intraoperative Pain Management on Postoperative Delirium in Elderly Patients
April 2025
Influence of Intraoperative Pain Management on Postoperative Delirium in Elderly Patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Influence of Intraoperative Pain Management on Postoperative Delirium in Elderly Patients: A Prospective Single-Center Randomized Controlled Trial.
Pain Ther . 2025 Feb;14(1):387-400.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Two hundred twenty-eight elderly patients undergoing unilateral total knee arthroplasty were randomized to receive either NOX-guided intraoperative analgesia (n=114) or routine monitoring based on BIS alone (n=114). The primary outcome was the incidence of postoperative delirium (POD) within 3 days post-surgery, assessed by the Confusion Assessment Method. Secondary outcomes included VAS pain scor...
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