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External Beam Radiation for HO Prevention After Acetabular Fracture Fixation

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April 2025

External Beam Radiation for HO Prevention After Acetabular Fracture Fixation

Vol: 307| Issue: 4| Number:32| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

The Use of External Beam Radiation Therapy for Heterotopic Ossification Prophylaxis After Surgical Fixation of Acetabular Fractures: A Randomized Controlled Trial.

J Orthop Trauma . 2025 Feb 1;39(2):e9-e13.

Contributing Authors:
A Boissonneault NN O'Hara GP Slobogean A Meyer M Maceroli MF Sciadini JW Nascone MJ Gage J Lin S Hanasoge J Shelton Z Rana M Mishra RV O'Toole

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Synopsis

One hundred four patients with displaced acetabular fractures surgically treated through a posterior or combined anterior-posterior approach were randomized to receive postoperative external beam radiation therapy (XRT; n=54) or no XRT (n=50). The primary outcome of interest was the incidence of severe heterotopic ossification (HO), defined as Brooker class III–IV. Secondary outcomes included any ...

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