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AAOS 2025: Vancomycin Bier Block Administration Vs Intravenous Prophylaxis
March 2025
AAOS 2025: Vancomycin Bier Block Administration Vs Intravenous Prophylaxis
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Tissue Concentrations of Vancomycin Achieved With Bier Block Administration Versus Intravenous Prophylaxis in Upper Extremity Surgery: A Randomized Controlled Trial
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CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
Twenty patients undergoing upper extremity reconstructive surgery were randomized to receive either regional IV perfusion of vancomycin (125 mg in 50 ml saline) (n=10) or systemic IV vancomycin (1 g) (n=10). The primary outcome of interest was the difference in vancomycin concentration in bone and fat tissue between the groups. Secondary outcomes of interest included tissue concentrations at vario...
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