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AAOS 2025: Fluoxetine Aids in the Reduction of Anxiety and Impoves of Sleep in an Trauma Population
March 2025
AAOS 2025: Fluoxetine Aids in the Reduction of Anxiety and Impoves of Sleep in an Trauma Population
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Fluoxetine Aids in the Reduction of Anxiety and Improvement of Sleep in an Orthopaedic Trauma Population
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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
Sixty-eight patients with high-energy orthopaedic trauma were randomized to receive fluoxetine (n=33) or calcium (n=35) for nine months. The primary outcome of interest was sleep efficiency, measured by the Pittsburgh Sleep Quality Index (PSQI). Secondary outcomes included overall sleep quality and anxiety levels, measured using the Beck Anxiety Inventory (BAI). Outcomes were assessed at six weeks...
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