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AAOS 2025: Oral Clonidine Reduces Bleeding in Pelvic & Acetabular Fracture Surgery
March 2025
AAOS 2025: Oral Clonidine Reduces Bleeding in Pelvic & Acetabular Fracture Surgery
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A
Oral Clonidine Reduces Bleeding in Pelvic and Acetabular Fractures Surgery: A Randomized Controlled Trial
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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Synopsis
Eighty-eight patients with pelvic or acetabular fractures were randomized to receive either 200 mcg of oral clonidine (n=44) or a placebo (n=44) 75 to 90 minutes before anesthesia. The primary outcome of interest was blood loss volume and the need for postoperative blood transfusion. Secondary outcomes included postoperative hemoglobin levels, postoperative pain, and the quality of the surgical vi...
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