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Efficacy of Generic Versus Branded Diacerein for Treatment of Knee Osteoarthritis
March 2025
Efficacy of Generic Versus Branded Diacerein for Treatment of Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of generic versus branded diacerein for treatment of knee osteoarthritis: A randomized control trial.
Medicine (Baltimore). 2024 Dec 6;103(49):e40810.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ninety-four patients with mild to moderate knee osteoarthritis were randomized to receive either 50 mg of generic diacerein (Diaceric®) (n=47) or branded diacerein (Artrodar®) (n=47) daily for 24 weeks. The primary outcome of interest was pain improvement measured by the visual analog scale (VAS) on motion. Secondary outcomes included patient-reported outcome measures (PROMs) such as the Western O...
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