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Topical Vancomycin For Reducing Surgical Site Infections After Spine Surgery: A Meta-Analysis
February 2025
Topical Vancomycin For Reducing Surgical Site Infections After Spine Surgery: A Meta-Analysis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Does the Application of Topical Vancomycin Reduce Surgical Site Infections in Spine Surgery? A Meta-analysis of Randomized Controlled Trials.
Clin Orthop Relat Res . 2024 Dec 1;482(12):2212-2219.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Six randomized controlled trials, including 2,140 patients undergoing spine surgery, were analyzed in this meta-analysis to compare the efficacy of topical vancomycin versus no vancomycin in preventing surgical site infections (SSIs). Pooled outcomes included the risk of overall SSIs, deep SSIs, and superficial SSIs. The results showed no significant difference in the rates of overall SSIs, deep S...
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