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Role of Pregabalin in Pain Management of Lower Limb Orthopedic Surgeries
January 2025
Role of Pregabalin in Pain Management of Lower Limb Orthopedic Surgeries
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Role of Pregabalin in Pre-Operative and Post-Operative Pain Management of Lower Limb Orthopedic Surgeries.
J Orthop Case Rep . 2024 Oct;14(10):263-269.Synopsis
Sixty patients undergoing lower limb orthopedic surgeries were randomized to receive either 150 mg pregabalin (n=30) or a placebo (n=30) two hours before surgery. The primary outcome was post-operative pain intensity measured by the Visual Analog Scale (VAS) at 6, 12, 24, and 48 hours. Secondary outcomes included total tramadol consumption over 48 hours and incidence of adverse effects. Pain inten...
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