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Platelet-Rich Plasma Versus Alternative Injections for Osteoarthritis of the Knee Pain & Function
January 2025
Platelet-Rich Plasma Versus Alternative Injections for Osteoarthritis of the Knee Pain & Function
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Platelet-Rich Plasma Versus Alternative Injections for Osteoarthritis of the Knee: A Systematic Review and Statistical Fragility Index-Based Meta-analysis of Randomized Controlled Trials.
Am J Sports Med . 2024 Oct;52(12):3147-3160.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
This systematic review and meta-analysis included 16 randomized controlled trials (RCTs) with a total of 1,993 patients with knee osteoarthritis. The study compared the effects of platelet-rich plasma (PRP) injections versus various nonoperative treatments, including hyaluronic acid (HA), corticosteroids, and saline. Pooled outcomes of interest were patient-reported symptom relief, pain improvemen...
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