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Intra-articular Injections of Ozone Versus Hyaluronic Acid for Knee Osteoarthritis Pain and Function

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Ace Report Cover
January 2025

Intra-articular Injections of Ozone Versus Hyaluronic Acid for Knee Osteoarthritis Pain and Function

Vol: 307| Issue: 1| Number:51| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Intra-articular injections of ozone versus hyaluronic acid for knee osteoarthritis: a level I meta-analysis.

Eur J Orthop Surg Traumatol . 2024 Nov 23;35(1):20.

Contributing Authors:
F Migliorini R Giorgino MG Mazzoleni L Schäfer FA Bertini N Maffulli

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Synopsis

Four randomized controlled trials involving 424 patients with knee osteoarthritis were included in this systematic review and meta-analysis comparing intra-articular injections of ozone versus hyaluronic acid. The outcomes of interest included visual analogue scale (VAS) scores and Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) scores. The pooled results demonstrated no signifi...

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