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Five Year Outcomes for Patients with Severe Fractures of the Lower Limb: WHIST Trial
January 2025
Five Year Outcomes for Patients with Severe Fractures of the Lower Limb: WHIST Trial
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Five-year outcomes for patients sustaining severe fractures of the lower limb from the Wound Healing in Surgery for Trauma (WHIST) trial.
Bone Joint J . 2024 Aug 1;106-B(8):858-864.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
1629 patients with complex lower limb fractures were randomized to receive negative pressure wound therapy (NPWT, n=813) or standard wound dressings (n=816) after surgical fixation. The primary outcome was the Disability Rating Index (DRI). Secondary outcomes included health-related quality of life (EQ-5D), pain (VAS), neuropathic pain (DN4), and complications. Outcomes were assessed annually for ...
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