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Phenylephrine vs Ephedrine On the Incidence of Postoperative Delirium in Olderly Adults
January 2025
Phenylephrine vs Ephedrine On the Incidence of Postoperative Delirium in Olderly Adults
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in olderly adults undergoing knee arthroplasty under general anesthesia: a single-center trial.
Sci Rep . 2024 Jul 27;14(1):17333.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred twenty elderly patients (aged 60–90 years) undergoing knee arthroplasty under general anesthesia were randomized to receive either ephedrine (n=60) or phenylephrine (n=60) to maintain intraoperative blood pressure. The primary outcome was the incidence of postoperative delirium (POD) within three days post-surgery. Secondary outcomes included changes in cardiac output (CO), regional ce...
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