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Intravenous Lidocaine and Pethidine for Pain Management in Patients with Femoral Bone Fracture
February 2025
Intravenous Lidocaine and Pethidine for Pain Management in Patients with Femoral Bone Fracture
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparing intravenous lidocaine and pethidine for pain management in emergency department patients with femoral bone fracture: a randomized controlled trial.
BMC Anesthesiol . 2024 Jul 23;24(1):250.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy-two patients with femoral bone fractures and severe pain were randomized to receive intravenous pethidine (25 mg, n=36) or intravenous lidocaine (3 mg/kg, not exceeding 200 mg, n=36) infused over 20 minutes. The primary outcome of interest was pain reduction based on the numerical rating scale (NRS) at multiple time points over 60 minutes. Secondary outcomes included the incidence of adver...
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