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Efficacy & safety of glucosamine sulfate, chondroitin sulfate, & combination for knee osteoarthritis

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Ace Report Cover
November 2024

Efficacy & safety of glucosamine sulfate, chondroitin sulfate, & combination for knee osteoarthritis

Vol: 306| Issue: 11| Number:84| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Evaluation of efficacy and safety of glucosamine sulfate, chondroitin sulfate, and their combination regimen in the management of knee osteoarthritis: a systematic review and meta-analysis.

Inflammopharmacology. 2024 01-Jun;():. 10.1007/s10787-024-01460-9

Contributing Authors:
A Rabade GL Viswanatha K Nandakumar A Kishore

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Synopsis

25 randomized controlled trials with adults diagnosed with knee osteoarthritis were included in this systematic review and meta-analysis comparing glucosamine sulfate, chondroitin sulfate, and their combination against placebo. The pooled outcomes evaluated pain intensity, physical function, joint stiffness, and joint space narrowing. Glucosamine sulfate significantly reduced joint space narrowing...

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