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Pre-Emptive Oxycodone, Diclofenac, and Gabapentin on Postoperative Pain After Tibia Fracture Surgery
March 2025
Pre-Emptive Oxycodone, Diclofenac, and Gabapentin on Postoperative Pain After Tibia Fracture Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparing the effects of pre-emptive oxycodone, diclofenac, and gabapentin on postoperative pain after tibia fracture surgery: A randomized clinical trial.
J West Afr Coll Surg . 2024 Jul-Sep;14(3):301-306.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred eleven patients undergoing tibia fracture surgery were randomized to receive pre-emptive analgesia with either oxycodone (n=37), gabapentin (n=37), or diclofenac (n=37). The primary outcome of interest was postoperative pain (POP) assessed at multiple time points up to 24 hours after surgery. Secondary outcomes included sedation levels, postoperative opioid analgesic consumption, and m...
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