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Opioid-Sparing Nonsteroid Anti-inflammatory Drugs Protocol for Tibial Shaft Fracture Nailing
March 2025
Opioid-Sparing Nonsteroid Anti-inflammatory Drugs Protocol for Tibial Shaft Fracture Nailing
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Opioid-Sparing Nonsteroid Anti-inflammatory Drugs Protocol in Patients Undergoing Intramedullary Nailing of Tibial Shaft Fractures: A Randomized Control Trial.
J Am Acad Orthop Surg. 2024 Jun 15;32(12):e596-e604.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Ninety-six patients with closed tibial shaft fractures were randomized to receive either an NSAID-based pain regimen (n=52) or an opioid-based pain regimen (n=44) following intramedullary nailing. The primary outcome of interest was opioid consumption, measured in morphine milligram equivalents (MMEs). Secondary outcomes included pain control assessed using the Visual Analog Scale (VAS) at 12-hour...
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