Intra-articular Injections of Hylan G-F 20 for Pain in Patients with Idiopathic Knee Osteoarthritis
Intra-articular Injections of Hylan G-F 20 for Pain in Patients with Idiopathic Knee Osteoarthritis
Three once-weekly intra-articular injections of Hylan G-F 20 significantly improve pain relief compared with placebo in patients with chronic idiopathic knee osteoarthritis: a single-centre, evaluator-blinded and patient-blinded, randomized controlled tri
Drugs Context. 2024 01-Apr;():. 10.7573/dic.2023-11-3Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Thirty patients with chronic idiopathic knee osteoarthritis (Larsen grade II or III) were randomized to receive three once-weekly intra-articular injections of either Hylan G-F 20 (n=15) or placebo (n=15). The primary outcome was pain relief as assessed by visual analogue scale (VAS) scores at weeks 12 and 26. Secondary outcomes included patient activity level, overall clinical condition, and adve...
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