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Systemic + Topical Tranexamic Acid for Total Knee Arthroplasty
August 2024
Systemic + Topical Tranexamic Acid for Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Evaluating the Efficacy and Safety of Combined Administration of Systemic and Topical Tranexamic Acid in Total Knee Arthroplasty.
J Orthop Case Rep . 2024 Apr;14(4):187-193.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Sixty-one patients with primary osteoarthritis of the knee were randomized to receive either intravenous TXA (n=30) or a combination of intravenous and intraarticular TXA (n=31). The primary outcome of interest was total blood loss (TBL). Secondary outcomes included a reduction in hemoglobin (Hb) levels, transfusion rates, and incidence of thromboembolic events (TE). Outcomes were assessed on the ...
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