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COA 2024: The Effect of Tourniquet Use on Local Tissue Concentrations of Cefazolin During TKA
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COA 2024: The Effect of Tourniquet Use on Local Tissue Concentrations of Cefazolin During TKA
Effect of Tourniquet on Local Tissue Concentrations of Cefazolin During Total Knee Arthroplasty: A Randomized Clinical Trial
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Synopsis
Sixty-one patients with primary total knee arthroplasty (TKA) were randomized to receive surgery with a tourniquet or without a tourniquet. The outcomes of interest included the local tissue concentration (LTC) of Cefazolin in fat, synovium, and bone, and the systemic concentration of Cefazolin in serum. Outcomes were assessed at regular intervals during surgery. Overall, the results of the study ...
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