COA 2024: Skin Antisepsis Solutions for Extremity Fractures (The PREPARE Trial)
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Synopsis
Eight thousand four hundred eighty-five patients with either closed (6785 patients) or open (1700 patients) extremity fractures were randomized to receive iodine povacrylex in alcohol or chlorhexidine gluconate in alcohol. The primary outcome of interest was the incidence of surgical site infections. Secondary outcomes included unplanned reoperation for fracture healing complications. Outcomes wer...
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