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COA 2024: Skin Antisepsis Solutions for Extremity Fractures (The PREPARE Trial)

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Ace Report Cover
June 2024

COA 2024: Skin Antisepsis Solutions for Extremity Fractures (The PREPARE Trial)

Vol: 306| Issue: 6| Number:5| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Skin Antisepsis Before Surgical Fixation of Extremity Fractures

Contributing Authors:
GP Slobogean S Sprague Investigators PREP-IT

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

Eight thousand four hundred eighty-five patients with either closed (6785 patients) or open (1700 patients) extremity fractures were randomized to receive iodine povacrylex in alcohol or chlorhexidine gluconate in alcohol. The primary outcome of interest was the incidence of surgical site infections. Secondary outcomes included unplanned reoperation for fracture healing complications. Outcomes wer...

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